Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Analyzing the relationship between decorrelation time and tissue thickness in acute rat brain slices using multispeckle diffusing wave spectroscopy

Not Accessible

Your library or personal account may give you access

Abstract

Novel techniques in the field of wavefront shaping have enabled light to be focused deep inside or through scattering media such as biological tissue. However, most of these demonstrations have been limited to thin, static samples since these techniques are very sensitive to changes in the arrangement of the scatterers within. As the samples of interest get thicker, the influence of the dynamic nature of the sample becomes even more pronounced and the window of time in which the wavefront solutions remain valid shrinks further. In this paper, we examine the time scales upon which this decorrelation happens in acute rat brain slices via multispeckle diffusing wave spectroscopy and investigate the relationship between this decorrelation time and the thickness of the sample using diffusing wave spectroscopy theory and Monte Carlo photon transport simulation.

© 2016 Optical Society of America

Full Article  |  PDF Article
More Like This
In vivo study of optical speckle decorrelation time across depths in the mouse brain

Muhammad Mohsin Qureshi, Joshua Brake, Hee-Jae Jeon, Haowen Ruan, Yan Liu, Abdul Mohaimen Safi, Tae Joong Eom, Changhuei Yang, and Euiheon Chung
Biomed. Opt. Express 8(11) 4855-4864 (2017)

Refractive index measurement of acute rat brain tissue slices using optical coherence tomography

Jingjing Sun, Sung Jin Lee, Lei Wu, Malisa Sarntinoranont, and Huikai Xie
Opt. Express 20(2) 1084-1095 (2012)

Fiber-based multispeckle detection for time-resolved diffusing-wave spectroscopy: characterization and application to blood flow detection in deep tissue

G. Dietsche, M. Ninck, C. Ortolf, J. Li, F. Jaillon, and T. Gisler
Appl. Opt. 46(35) 8506-8514 (2007)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (4)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved