Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Wide-Field Confocal Interferometric Backscattering (iSCAT)-Raman Microscopy

Not Accessible

Your library or personal account may give you access


We describe a novel instrument combining interferometric scattering microscopy (iSCAT) with confocal Raman microscopy. This system images the refractive index morphology of a complex material on a 200 nm length scale over a 100 µm wide-field sampled at a frequency exceeding 50 frames per second. Co-axial Raman sampling provides point-by-point label-free chemical information of selected features with a similar degree of spatial resolution and a high degree of reproducibility. This system offers promise for the non-destructive label-free classification of a wide range of natural materials.

© 2015 Optical Society of America

PDF Article
More Like This
Nanoscale Imaging of Live Cells with Confocal Interferometric Scattering Microscopy (iSCAT)

Michelle Küppers, David Albrecht, Anna Kashkanova, Jennifer Lühr, and Vahid Sandoghdar
MTu4A.1 Microscopy Histopathology and Analytics (Microscopy) 2022

Label-Free Confocal iSCAT Microscopy on Live Cells

Michelle Küppers, David Albrecht, Anna Kashkanova, Jennifer Lühr, and Vahid Sandoghdar
NTh2C.5 Novel Techniques in Microscopy (NTM) 2021

Label-Free Live-Cell Imaging with Interferometric Scattering Microscopy: Confocal Imaging and High-Speed 3D Single Particle Tracking

Michelle Küppers, Anna Kashkanova, Jennifer Lühr, David Albrecht, Alexandra Schambony, and Vahid Sandoghdar
MW1A.4 Microscopy Histopathology and Analytics (Microscopy) 2020


You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
Login to access Optica Member Subscription

Select as filters

Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved