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High Contrast Interferometric Second Harmonic Generation Microscopy Probes the Polarity of Fibrils in Complex Collagenous Tissues

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We implemented for the first time Interferometric SHG microscopy, using femtosecond pulses, to image the relative fibrils polarity in cartilage and show that SHG intensity depends on the local ratio of fibrils with opposite polarities.

© 2015 Optical Society of America

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