Carbon Nanotube Assisted Laser Thermotherapy of Skin Cancers – Pilot Proof-of-Principle Study in a Murine Model

Naiyan Huang; Naiyan Huang; Naiyan Huang; Hequn Wang; Hequn Wang; Jianhua Zhao; Harvey Lui; Mladen Korbelik; Haishan Zeng; Haishan Zeng

doi:10.1364/ACP.2009.ThGG3

Asia Communications and Photonics Conference and Exhibition
Technical Digest (CD) (Optica Publishing Group, 2009),
paper ThGG3
•https://doi.org/10.1364/ACP.2009.ThGG3

Carbon Nanotube Assisted Laser Thermotherapy of Skin Cancers – Pilot Proof-of-Principle Study in a Murine Model

Naiyan Huang, Hequn Wang, Jianhua Zhao, Harvey Lui, Mladen Korbelik, and Haishan Zeng

Asia Communications and Photonics Conference and Exhibition 2009

Shanghai China
2–6 November 2009
ISBN: 978-1-55752-877-3

From the session
Nano-biophotonics for Imaging and Therapy II (ThGG)

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N. Huang, H. Wang, J. Zhao, H. Lui, M. Korbelik, and H. Zeng, "Carbon Nanotube Assisted Laser Thermotherapy of Skin Cancers – Pilot Proof-of-Principle Study in a Murine Model," in Asia Communications and Photonics Conference and Exhibition, Technical Digest (CD) (Optica Publishing Group, 2009), paper ThGG3.

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Abstract

Ten groups of mice were exposed to 785 nm laser after intratumoral injection of single-wall carbon nanotubes (SWNTs). The temperature within the tumors increased in a light- and drug-dose dependent manner; optimized light and drug dose combinations resulted in eradication of skin tumors. SWNTs persisted within the tumor tissue for months.

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