Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy

Shuangmu Zhuo; Jianxin Chen; Shusen Xie; Xingshan Jiang; Liqin Zheng

doi:10.1364/ACP.2009.WL88

Asia Communications and Photonics Conference and Exhibition
Technical Digest (CD) (Optica Publishing Group, 2009),
paper WL88
•https://doi.org/10.1364/ACP.2009.WL88

Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy

Shuangmu Zhuo, Jianxin Chen, Shusen Xie, Xingshan Jiang, and Liqin Zheng

Asia Communications and Photonics Conference and Exhibition 2009

Shanghai China
2–6 November 2009
ISBN: 978-1-55752-877-3

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S. Zhuo, J. Chen, S. Xie, X. Jiang, and L. Zheng, "Imaging of matrix-disorder in normal and pathological human dermis using nonlinear optical microscopy," in Asia Communications and Photonics Conference and Exhibition, Technical Digest (CD) (Optica Publishing Group, 2009), paper WL88.

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Abstract

In dermis, collagen and elastin are important structural proteins of extracellular maxtrix. The matrix-disorder is associated with various physiologic processes, such as localized scleroderma, anetoderma, photoaging. In this work, we demonstrate the capability of nonlinear optical microscopy in imaging structural proteins in normal and pathological human dermis.

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