Abstract
Dynamic contrast enhanced (DCE) MRI is the method of choice for clinical tumor detection. There are three categories of DCE-MRI analysis methods including qualitative DCE-MRI, semi-quantitative DCE-MRI, and quantitative DCE-MRI. Among these three categories, quantitative DCE-MRI is the only one that could provide pharmacokinetic parameters and directly reveal physiological state of tumor. In this paper, we have made a brief review on quantitative DCE-MRI. Firstly, physiological basis of DCE-MRI was described in details. Then, two kinds of contrast agent, low molecular weighted contrast media (LMCM) and macromolecular contrast media (MMCM), are introduced respectively. After that, several T1 weighted DCE-MRI data analysis methods are introduced, too. At last, possible further developments of DCE-MRI have been discussed.
© 2011 Optical Society of America
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