Hepatocellular carcinoma cells Raman spectra with gold and silver colloid as SERS substrate

Hongfei Zhu; Shupeng Liu; Ling Hu; Wei Zhang; Chen Qian; Zhenyi Chen; Na Chen

doi:10.1364/ACP.2011.83112M

Optical Sensors and Biophotonics
Proceedings of SPIE (Optica Publishing Group, 2011),
paper 83112M
•https://doi.org/10.1364/ACP.2011.83112M

Hepatocellular carcinoma cells Raman spectra with gold and silver colloid as SERS substrate

Hongfei Zhu, Shupeng Liu, Ling Hu, Wei Zhang, Chen Qian, Zhenyi Chen, and Na Chen

Asia Communications and Photonics Conference and Exhibition 2011

Shanghai China
13–16 November 2011
ISBN: 978-0-8194-8959-3

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H. Zhu, S. Liu, L. Hu, W. Zhang, C. Qian, Z. Chen, and N. Chen, "Hepatocellular carcinoma cells Raman spectra with gold and silver colloid as SERS substrate," in Optical Sensors and Biophotonics, J. Popp, D. Matthews, J. Tian, and C. Yang, eds., Vol. 8311 of Proceedings of SPIE (Optica Publishing Group, 2011), paper 83112M.

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Abstract

In this paper, Raman spectra of hepatocellular carcinoma cells were analyzed using gold and silver nanoparticles as SERS active substrates. The size of gold and silver nanoparticles is about 50-60 nm, and these nanoparticles have enhancement role to the Raman spectrum of hepatocellular carcinoma cells. The results show that the Raman enhancement effects of gold colloid are more sensitive than silver colloid to cells.

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