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Theoretical and numerical assessment of photon migration in blood layers in regard to red cell aggregation measurements by light backscattering technique

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Abstract

New method is proposed to calculate light scattering angular distributions resulting from photon migration in multiply scattering layers of concentrated suspensions of large particles of different sizes, shapes, and orientations, modeling the aggregating red blood cells. Results are in good agreement with Monte-Carlo simulations of the similar process. Both approaches are used to model the time course of backscattered light intensity, related to the experimentally measured spontaneous aggregation kinetics.

© 2002 Optical Society of America

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