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Assessment of the detection sensitivity of bioluminescent and fluorescent reporters in small animal models

T.L. Troy, O. Delage, and B.W. Rice

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Abstract

An absolutely calibrated imaging system that can detect the steady-state emission from bioluminescent and/or fluorescent probes located inside small animals is described. Techniques to improve in vivo detection sensitivity of fluorescent imaging are explored.

© 2004 Optical Society of America

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