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Complex optical assessment of hemorheologic and microcirculatory disorders by means of imaging and laser diffraction techniques

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Abstract

Hemorheologic disorders are frequently caused by enhanced aggregation and reduced deformability of erythrocytes. The former case can be characterized by the erythrocyte sedimentation rate (ESR) and position of the red blood/plasma boundary location with the help of ESR-scan - an automatic scanning device for high-temporal resolution imaging of the process of red blood sedimentation providing a much higher, comparing with traditional test, precision and accuracy of measurements. In this device, the diagnostic information is contained in the plots describing the time evolution of the boundary position respective to the initial position of the blood/air interface, sedimentogram, and in the velocity versus time plots, the ESR-grams [1].

© 2004 Optical Society of America

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