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Modelling of indocyanine green boluses with a finite element model of the adult human head and the Fick principle

Terence S. Leung, Ilias Tachtsidis, Clare E. Elwell, David T. Delpy, Martin Tisdall, Martin Smith, and Simon R. Arridge

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Abstract

Using the Fick principle and a finite element model of light distribution, ICG boluses were simulated in a head model, showing measurable changes in cerebral blood flow using NIR surface measurements despite the superficial contamination.

© 2006 Optical Society of America

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