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Breast Tumor Biochemical Responses to Neoadjuvant Chemotherapy can be Observed Using Diffuse Optical Spectroscopy

Albert Cerussi, Natasha Shah, Montana Compton, Amanda Durkin, Bruce Tromberg, David Hsiang, Rita Mehta, Choong Baick, and John Butler

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Abstract

Non-invasive measurements of near-infrared absorption and scattering coefficients reveal important early physiologic changes in tumors in response to pre-surgical (neoadjuvant) chemotherapy. Such early biochemical changes could be used to predict final pathological outcome

© 2006 Optical Society of America

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