Fluorescence Lifetime Imaging Microscopy Detects Altered Metabolic Function in Living Human Cancer Cell Models

Dhruv Sud; Wei Zhong; David Beer; David Beer; Mary-Ann Mycek; Mary-Ann Mycek; Mary-Ann Mycek

doi:10.1364/BIO.2006.TuC6

Biomedical Optics
Technical Digest (CD) (Optica Publishing Group, 2006),
paper TuC6
•https://doi.org/10.1364/BIO.2006.TuC6

Fluorescence Lifetime Imaging Microscopy Detects Altered Metabolic Function in Living Human Cancer Cell Models

Dhruv Sud, Wei Zhong, David Beer, and Mary-Ann Mycek

Biomedical Topical Meeting 2006

Fort Lauderdale, Florida United States
19–22 March 2006
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Molecular Imaging and Drug Discovery (TuC)

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D. Sud, W. Zhong, D. Beer, and M. Mycek, "Fluorescence Lifetime Imaging Microscopy Detects Altered Metabolic Function in Living Human Cancer Cell Models," in Biomedical Optics, Technical Digest (CD) (Optica Publishing Group, 2006), paper TuC6.

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Abstract

A unique FLIM system sensed key molecules involved in metabolic pathways in living cellular models of human esophageal cancer progression. Functional imaging studies revealed endogenous, optical biomarkers that are clinically detectable in human tissue.

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