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A Direct Linear Reconstruction Method for Spectrally Resolved 3D Bioluminescence Tomography

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Abstract

Spectrally-resolved BioLuminescence optical Tomography (sBLT) is used to recover images of Luciferase activity within a 3D mouse model using multi-wavelength emission data from multiple internal bioluminescence sources. The images show that the location of sources can be reconstructed accurately using a fast, direct and linear reconstruction algorithm.

© 2006 Optical Society of America

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