Investigating Cross-talk in Cytochrome C Oxidase Concentration Quantification using Near Infrared Spectroscopy in a Two-layered Model

Terence S. Leung; Ilias Tachtsidis; Clare E. Elwell; Martin Tisdall; Caroline Pritchard; Martin Smith; Chris Cooper

doi:10.1364/BIOMED.2008.BSuE77

Biomedical Optics
OSA Technical Digest (CD) (Optica Publishing Group, 2008),
paper BSuE77
•https://doi.org/10.1364/BIOMED.2008.BSuE77

Investigating Cross-talk in Cytochrome C Oxidase Concentration Quantification using Near Infrared Spectroscopy in a Two-layered Model

Terence S. Leung, Ilias Tachtsidis, Clare E. Elwell, Martin Tisdall, Caroline Pritchard, Martin Smith, and Chris Cooper

Biomedical Optics 2008

St. Petersburg, Florida United States
16–19 March 2008
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BIOMED Poster Session I (BSuE)

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T. S. Leung, I. Tachtsidis, C. E. Elwell, M. Tisdall, C. Pritchard, M. Smith, and C. Cooper, "Investigating Cross-talk in Cytochrome C Oxidase Concentration Quantification using Near Infrared Spectroscopy in a Two-layered Model," in Biomedical Optics, OSA Technical Digest (CD) (Optica Publishing Group, 2008), paper BSuE77.

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Abstract

The cross-talk issue in the quantification of concentration changes in oxidized cytochrome c oxidase in the human head has been investigated using a two layered model representing the scalp/skull and brain layers. The results showed that the degree of cross-talk can be reduced by using increased number of wavelengths and with wavelength dependent path length correction.

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