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Optical Biomarkers Associated with the Invasive Potential of Tumor Cells in Engineered Tissue Models

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Abstract

Intrinsic two-photon excited fluorescence (TPEF) images of epithelial tumor cells embedded in collagen matrices reveal distinct morphologies and organization from the subcellular to the tissue level associated with motility and invasive potential of cells.

© 2010 Optical Society of America

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