Concurrent MRI and Diffuse Correlation &amp; Near-Infrared Spectroscopic Measurement of Cerebral Hemodynamic Response to Hypercapnia and Hyperoxia

Turgut Durduran; Turgut Durduran; Turgut Durduran; David L Minkoff; Meeri N Kim; Dalton Hance; Erin M Buckley; Mari Tobita; Jiongjiong Wang; Joel H Greenberg; John A Detre; John A Detre; Arjun G Yodh

doi:10.1364/BIOMED.2010.BTuB2

Biomedical Optics and 3-D Imaging
OSA Technical Digest (CD) (Optica Publishing Group, 2010),
paper BTuB2
•https://doi.org/10.1364/BIOMED.2010.BTuB2

Concurrent MRI and Diffuse Correlation & Near-Infrared Spectroscopic Measurement of Cerebral Hemodynamic Response to Hypercapnia and Hyperoxia

Turgut Durduran, David L Minkoff, Meeri N Kim, Dalton Hance, Erin M Buckley, Mari Tobita, Jiongjiong Wang, Joel H Greenberg, John A Detre, and Arjun G Yodh

Biomedical Optics 2010

Miami, Florida United States
11–14 April 2010
ISBN: 978-1-55752-887-2

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Brain Monitoring and Imaging I (BTuB)

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T. Durduran, D. L. Minkoff, M. N. Kim, D. Hance, E. M. Buckley, M. Tobita, J. Wang, J. H. Greenberg, J. A. Detre, and A. G. Yodh, "Concurrent MRI and Diffuse Correlation & Near-Infrared Spectroscopic Measurement of Cerebral Hemodynamic Response to Hypercapnia and Hyperoxia," in Biomedical Optics and 3-D Imaging, OSA Technical Digest (CD) (Optica Publishing Group, 2010), paper BTuB2.

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Abstract

We study the effects of hypercapnia and hyperoxia in cerebral hemodynamics of healty adults using concurrent ASL and BOLD MRI, diffuse correlation (DCS) & near-infrared spectroscopies (NIRS). Our aim was to validate ASL vs DCS, compare BOLD response to NIRS results and compare estimates of CMRO₂ by two methods.

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