Abstract
The back-reflected photons from samples in optical-resolution photoacoustic microscopy are usually discarded and the optical scattering information carried by these photons is therefore ignored. By employing a 2×2 single-mode fiber optical coupler in a laser-scanning optical-resolution photoacoustic microscope for delivering the illuminating laser light and collecting the back reflected photons, a fiber-optic confocal microscope is integrated with the photoacoustic microscope. Hence, simultaneous multimodal imaging can be achieved with a single light source and images from the two modalities are intrinsically registered. Such capabilities are demonstrated in imaging both phantoms and small animals in vivo.
© 2010 Optical Society of America
PDF ArticleMore Like This
Hao F. Zhang and Shuliang Jiao
BWE4 Biomedical Optics (BIOMED) 2010
Li Li, Bin Rao, Vassiliy Tsytsarev, and Lihong V. Wang
BWE3 Biomedical Optics (BIOMED) 2010
Song Hu, Konstantin Maslov, and Lihong V. Wang
BWE5 Biomedical Optics (BIOMED) 2010