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Conferences > BIOMED > 2012 > BSu2B > BSu2B.6

Non-invasive Optical Detection of Cell Differentiation Status Using Endogenous Sources of Optical Contrast

Kyle P. Quinn, Rebecca Scholl Hayden, David L. Kaplan, and Irene Georgakoudi

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Abstract

Two-photon fluorescence and second harmonic generation images of mesenchymal stem cells undergoing osteoblastic differentiation demonstrate the cell redox ratio of FAD/(NADH+FAD) can serve as non-invasive biomarker of cell differentiation status.

© 2012 Optical Society of America

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