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Wide-field Mesh-based Monte Carlo method in time-domain Fluorescence Molecular Tomography

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Abstract

We evaluated the potential of mesh-based Monte Carlo method for wide-field time-gated fluorescence molecular tomography (FMT) in preclinical settings with the goal to overcome the inaccuracy of the diffusion equation in these scenarios. The mesh-based parallel code was optimized to utilize multiple threads and nodes for efficient computations. The in silico results established that, the optimized mesh-based Monte Carlo method is a computationally efficient solution for optical tomography for pre-clinical studies.

© 2012 Optical Society of America

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