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Ultra-structural mutations in epithelium and stroma in colorectal cancer field carcinogenesis and their potential biological mechanisms

Ji Yi, Andrew J. Radosevich, Yolanda Stypula-Cyrus, Nikhil N. Mutyal, Samira Michelle Azarin, Hemant K. Roy, and Vadim Backman

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Abstract

The detection of ultra-structural mutations emerges as a powerful method for colorectal cancer screening. Here we used inverse spectroscopic optical coherence tomography to identify ultra-structural mutations in epithelium and stroma, and explore potential biological mechanisms.

© 2014 Optical Society of America

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