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Cerebral Blood Flow Monitoring in Preterm Infants by Diffuse Correlation Spectroscopy

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Continuous monitoring of cerebral blood flow (CBF) at the bedside has the potential to reduce the incidence of ischemic brain injury and improve long-term outcome in high-risk preterm infants. This study investigated the ability of diffuse correlation spectroscopy (DCS) to monitor CBF in preterm infants. Measurements were acquired in five preterm neonates undergoing indomethacin treatment of patent ductus arteriosus. Reduction in CBF measured by DCS was 27±7% (mean±SD) from baseline, in agreement with previously reported values obtained by other modalities.

© 2014 Optical Society of America

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