The Role of Nuclear Nano-Environment on DNA Dehybridization

Luay Matthew Almassalha; Lusik Cherkezyan; Greg Putzel; Vadim Backman; Igal Szleifer

doi:10.1364/BIOMED.2014.BT3A.39

Biomedical Optics 2014
OSA Technical Digest (online) (Optica Publishing Group, 2014),
paper BT3A.39
•https://doi.org/10.1364/BIOMED.2014.BT3A.39

The Role of Nuclear Nano-Environment on DNA Dehybridization

Luay Matthew Almassalha, Lusik Cherkezyan, Greg Putzel, Vadim Backman, and Igal Szleifer

Biomedical Optics 2014

Miami, Florida United States
26–30 April 2014
ISBN: 978-1-55752-997-8

From the session
Poster Session III (BT3A)

Not Accessible

Your library or personal account may give you access

Get PDF
Email
Share
Get Citation
Copy Citation Text
L. M. Almassalha, L. Cherkezyan, G. Putzel, V. Backman, and I. Szleifer, "The Role of Nuclear Nano-Environment on DNA Dehybridization," in Biomedical Optics 2014, OSA Technical Digest (online) (Optica Publishing Group, 2014), paper BT3A.39.

Export Citation
- BibTex
- Endnote (RIS)
- HTML
- Plain Text
Citation alert
Save article

Abstract

Using coarse-grain molecular dynamics simulations and UV spectroscopy, we study the role of the macromolecular crowding on the structure of double stranded DNA. Our results show that crowding has a non-monotonic influence on DNA dehybridization.

PDF Article

More Like This

Macromolecular Crowding as a Regulator of Transcription

Igal Szleifer
BM4A.7 Biomedical Optics (BIOMED) 2014

Assessment of Nuclear Nano-morphology Markers for Predicting Cancer Progression Risk in Patients with Precancerous Breast Lesions

Yang Liu, Kevin Staton, Shikhar Uttam, Rohit Bhargava, Zaibo Li, Hong Wang, Randall E. Brand, Atilla Soran, and Gretchen M. Ahrendt
BW1A.4 Biomedical Optics (BIOMED) 2014

Using Tunable Nanoscale Confinement to Image and Manipulate DNA

Daniel Berard, Jason S. Leith, Francois Michaud, and Sabrina R. Leslie
SeM4C.3 Optical Sensors (Sensors) 2014

Previous Article Next Article