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Biodistribution study of 2-nitroimidazole indocyanine green conjugate dye conjugates

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Abstract

Using a fluorescence imager we studied the biodistribution of a new hypoxia probe, piperazine-2-nitroimidazole-ICG in murine tumor models. Piperazine-2-nitroimidazole-ICG showed much higher fluorescence intensity and tumor retention in comparison with its predecessors.

© 2014 Optical Society of America

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