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Reduction in Nanoparticle Size Dramatically Improves Plasmonic Photo-thermal Therapy Efficacy in Aggressive Triple Negative Breast Cancer

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Abstract

We report 4X enhancement of tumor accumulation and 2X increase in post photo-thermal therapy survival for 100nm Gold Nanomatryushkas versus conventional 150nm silica core gold nanoshells in mice with xenografted human triple negative breast cancer.

© 2014 Optical Society of America

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