Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Computed optical interferometric tomography for high-speed volumetric cellular imaging

Not Accessible

Your library or personal account may give you access

Abstract

Three-dimensional high resolution imaging methods are important for cellular level research. Optical coherence microscopy (OCM) is a scattering-based technology for cellular imaging with both high axial and lateral resolution. With a high numerical aperture objective, OCM has a shallow depth-of-field and requires scanning the focus through the entire region of interest to perform volumetric imaging. Interferometric synthetic aperture microscopy (ISAM) and computational adaptive optics (CAO) are computed imaging techniques that overcome the depth-of-field limitation and the effect of optical aberrations in optical coherence tomography (OCT), respectively. In this work we combine ISAM/CAO and OCM to achieve high-speed volumetric cellular imaging. Ex vivo images of human breast tissue and rat brain tissue are presented.

© 2014 Optical Society of America

PDF Article  |   Presentation Video
More Like This
Interferometric Synthetic Aperture Microscopy with Computational Adaptive Optics for High-Resolution Tomography of Scattering Tissue

Steven G. Adie, Adeel Ahmad, Nathan Shemonski, Benedikt W. Graf, Heeseok Kim, Wen-Mei W. Hwu, P. Scott Carney, and Stephen A. Boppart
BW2A.1 Biomedical Optics (BIOMED) 2012

Broadband optical interferometric tomography with computational adaptive optics using ‘guide stars’

Steven G. Adie, Nathan Shemonski, Benedikt W. Graf, Adeel Ahmad, P. Scott Carney, and Stephen A. Boppart
FM3D.3 Frontiers in Optics (FiO) 2012

Polarimetric Interferometric Synthetic Aperture Microscopy: Vectorial Computed Imaging from Optical Coherence Tomography Data

Brynmor J. Davis, Tyler S. Ralston, Daniel L. Marks, Stephen A. Boppart, and P. Scott Carney
CMD8 Computational Optical Sensing and Imaging (COSI) 2007

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Presentation Video

Presentation video access is available to:

  1. Optica Publishing Group subscribers
  2. Technical meeting attendees
  3. Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads


More Like This
Interferometric Synthetic Aperture Microscopy with Computational Adaptive Optics for High-Resolution Tomography of Scattering Tissue

Steven G. Adie, Adeel Ahmad, Nathan Shemonski, Benedikt W. Graf, Heeseok Kim, Wen-Mei W. Hwu, P. Scott Carney, and Stephen A. Boppart
BW2A.1 Biomedical Optics (BIOMED) 2012

Broadband optical interferometric tomography with computational adaptive optics using ‘guide stars’

Steven G. Adie, Nathan Shemonski, Benedikt W. Graf, Adeel Ahmad, P. Scott Carney, and Stephen A. Boppart
FM3D.3 Frontiers in Optics (FiO) 2012

Polarimetric Interferometric Synthetic Aperture Microscopy: Vectorial Computed Imaging from Optical Coherence Tomography Data

Brynmor J. Davis, Tyler S. Ralston, Daniel L. Marks, Stephen A. Boppart, and P. Scott Carney
CMD8 Computational Optical Sensing and Imaging (COSI) 2007

Select as filters


Select Topics Cancel
© Copyright 2022 | Optica Publishing Group. All Rights Reserved