Single-Molecule, Real-Time (SMRT™) Monitoring of Biomolecules

Jonas Korlach

doi:10.1364/BODA.2011.BWC1

Optics in the Life Sciences
OSA Technical Digest (CD) (Optica Publishing Group, 2011),
paper BWC1
•https://doi.org/10.1364/BODA.2011.BWC1

Single-Molecule, Real-Time (SMRT™) Monitoring of Biomolecules

Jonas Korlach

Bio-Optics: Design and Application 2011

Monterey, California United States
4–6 April 2011
ISBN: 978-1-55752-909-1

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Spectroscopic Imaging (BWC)

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J. Korlach, "Single-Molecule, Real-Time (SMRT™) Monitoring of Biomolecules," in Optics in the Life Sciences, OSA Technical Digest (CD) (Optica Publishing Group, 2011), paper BWC1.

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Abstract

The use of zero-mode waveguides - photonic observation volume confinement nanostructures – and instrumentation is described for allowing single-molecule, real-time biomolecular analysis, with biotechnological applications such as rapid DNA sequencing.

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