Polarization Properties of Amyloid Beta in the Retina of the Eye as a Biomarker of Alzheimer’s Disease

Melanie C.W. Campbell; Melanie C.W. Campbell; Melanie C.W. Campbell; David De Vries; Laura Emptage; Chris Cookson; Marsha Kisilak; Marsha Kisilak; Juan M. Bueno; Francisco J. Avila; Francisco J. Avila

doi:10.1364/BODA.2015.BM3A.4

Optics in the Life Sciences
OSA Technical Digest (online) (Optica Publishing Group, 2015),
paper BM3A.4
•https://doi.org/10.1364/BODA.2015.BM3A.4

Polarization Properties of Amyloid Beta in the Retina of the Eye as a Biomarker of Alzheimer’s Disease

Melanie C.W. Campbell, David De Vries, Laura Emptage, Chris Cookson, Marsha Kisilak, Juan M. Bueno, and Francisco J. Avila

Bio-Optics: Design and Application 2015

Vancouver Canada
12–15 April 2015
ISBN: 978-1-55752-954-1

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New Approaches for Optical Diagnostics (BM3A)

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M. C. W. Campbell, D. De Vries, L. Emptage, C. Cookson, M. Kisilak, J. M. Bueno, and F. J. Avila, "Polarization Properties of Amyloid Beta in the Retina of the Eye as a Biomarker of Alzheimer’s Disease," in Optics in the Life Sciences, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper BM3A.4.

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Abstract

Polarimetry was performed on amyloid deposits (thioflavin S positive) in human postmortem retinas of those with a diagnosis of Alzheimer's disease. Mueller matrix properties and polarization contrast of this biomarker show promise as a non-invasive diagnostic.

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