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An endoscopic imaging system for co-registered Doppler optical coherence tomography and autofluorescence imaging of human airways in vivo

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Abstract

This work reports a fiber optic-based endoscopic imaging system capable of combined Doppler optical coherence tomography (DOCT) and autofluorescence (AF) imaging. The two key components in this dual-modality imaging system are a specially designed three-port wavelength multiplexing fiber optic rotary joint (FORJ) and a custom 900 µm diameter double-clad fiber (DCF) catheter. The three-port FORJ combines the two imaging modalities efficiently with more than 83% throughput for collected AF emission and the DCF catheter allows endoscopic coregistered DOCT and AF imaging. Endoscopic DOCT and AF imaging of small human airways in vivo is presented to demonstrate the performance of the system.

© 2015 Optical Society of America

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