Label-free Multimodal Nonlinear Optical Imaging of Needle Biopsies: Towards Real-time Monitoring of Living Biopsies

Lingxiao Yang; Lingxiao Yang; Jaena Park; Jaena Park; Carlos Renteria; Carlos Renteria; Eric J. Chaney; Marina Marjanovic; Marina Marjanovic; Heidi Philips; Stephen A. Boppart; Stephen A. Boppart; Stephen A. Boppart

doi:10.1364/BODA.2021.DF2A.3

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper DF2A.3
•https://doi.org/10.1364/BODA.2021.DF2A.3

Label-free Multimodal Nonlinear Optical Imaging of Needle Biopsies: Towards Real-time Monitoring of Living Biopsies

Lingxiao Yang, Jaena Park, Carlos Renteria, Eric J. Chaney, Marina Marjanovic, Heidi Philips, and Stephen A. Boppart

Bio-Optics: Design and Application 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Nonlinear Optical Processes and Applications (DF2A)

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L. Yang, J. Park, C. Renteria, E. J. Chaney, M. Marjanovic, H. Philips, and S. A. Boppart, "Label-free Multimodal Nonlinear Optical Imaging of Needle Biopsies: Towards Real-time Monitoring of Living Biopsies," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper DF2A.3.

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Abstract

A portable label-free multimodal nonlinear optical imaging platform has been developed and demonstrated for intraoperative imaging of needle biopsies in canine cancer surgeries, with investigations on the integrity of freshly excised biopsies over time.

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