The Effect of Scattering on Spatial Resolution of Raman Spectroscopy in Tissue

Jordyn Hales; Jessica Jones; Dustin Shipp

doi:10.1364/BODA.2021.DW3A.7

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper DW3A.7
•https://doi.org/10.1364/BODA.2021.DW3A.7

The Effect of Scattering on Spatial Resolution of Raman Spectroscopy in Tissue

Jordyn Hales, Jessica Jones, and Dustin Shipp

Bio-Optics: Design and Application 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Spectroscopy (DW3A)

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J. Hales, J. Jones, and D. Shipp, "The Effect of Scattering on Spatial Resolution of Raman Spectroscopy in Tissue," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper DW3A.7.

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Abstract

We present a study to determine the minimum spatial sampling resolution required to detect cancer cells. We compare results from Monte Carlo simulations and experiments using beads embedded in tissue phantoms with varying scattering properties.

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