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Conferences > BOSD > 1996 > FT > FT3

Nitrogen Laser Excited Autofluorescence Spectroscopy for Discrimination of Human Breast Malignancy

S.K. Majumder, A. Uppal, and P.K. Gupta

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Abstract

The results of our in-vitro studies on N2 laser excited autofluorescence from pathologically characterized cancerous and adjoining normal human breast tissues obtained after resection from 15 patients with breast cancer are presented. A 6-variable multivariate linear regression (MVLR) analysis used for maximizing discrimination between tissue types resulted in a sensitivity of 85.5% and a specificity of 87.07% towards cancer for unpaired comparison and a sensitivity of 93.1% and specificity of 87.1% for paired comparison of the tissue spectra.

© 1996 Optical Society of America

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