Optogenetic Control of Neural Activity with Time-Reversed Ultrasound Encoded Light

Haowen Ruan; Joshua Brake; J. Elliott Robinson; Mooseok Jang; Cheng Xiao; Chunyi Zhou; Viviana Gradinaru; Changhuei Yang; Changhuei Yang

doi:10.1364/BRAIN.2017.BrM3B.3

Optics in the Life Sciences Congress
OSA Technical Digest (online) (Optica Publishing Group, 2017),
paper BrM3B.3
•https://doi.org/10.1364/BRAIN.2017.BrM3B.3

Optogenetic Control of Neural Activity with Time-Reversed Ultrasound Encoded Light

Haowen Ruan, Joshua Brake, J. Elliott Robinson, Mooseok Jang, Cheng Xiao, Chunyi Zhou, Viviana Gradinaru, and Changhuei Yang

Optics and the Brain 2017

San Diego, California United States
2–5 April 2017
ISBN: 978-1-943580-25-5

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Point and Shoot (Patterned Illumination and Optogenetics) (BrM3B)

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H. Ruan, J. Brake, J. E. Robinson, M. Jang, C. Xiao, C. Zhou, V. Gradinaru, and C. Yang, "Optogenetic Control of Neural Activity with Time-Reversed Ultrasound Encoded Light," in Optics in the Life Sciences Congress, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper BrM3B.3.

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Abstract

We developed an optical technique that can focus light multi-millimeter deep inside biological tissue noninvasively. We demonstrated that this technique enables optogenetic control of individual neurons in brain slices.

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