Mesoscopic cortical calcium dynamics during wakefulness, natural sleep, and anesthesia

Lindsey M. Brier; Eric C. Landsness; Patrick W. Wright; Adam Q. Bauer; Grant Baxter; Jin-Moo Lee; Joseph P. Culver; Joseph P. Culver; Joseph P. Culver

doi:10.1364/BRAIN.2017.BrS1B.2

Optics in the Life Sciences Congress
OSA Technical Digest (online) (Optica Publishing Group, 2017),
paper BrS1B.2
•https://doi.org/10.1364/BRAIN.2017.BrS1B.2

Mesoscopic cortical calcium dynamics during wakefulness, natural sleep, and anesthesia

Lindsey M. Brier, Eric C. Landsness, Patrick W. Wright, Adam Q. Bauer, Grant Baxter, Jin-Moo Lee, and Joseph P. Culver

Optics and the Brain 2017

San Diego, California United States
2–5 April 2017
ISBN: 978-1-943580-25-5

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Analyzing Circuitry, Network Function, and Information Processing (BrS1B)

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L. M. Brier, E. C. Landsness, P. W. Wright, A. Q. Bauer, G. Baxter, J. Lee, and J. P. Culver, "Mesoscopic cortical calcium dynamics during wakefulness, natural sleep, and anesthesia," in Optics in the Life Sciences Congress, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper BrS1B.2.

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Abstract

Using a GCaMP6 transgenic mouse model, mesoscopic-imaging shows an anterior to posterior propagation of delta neuronal activity during both spontaneous sleep and anesthesia that is absent during wakefulness and alters functional connectivity.

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