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Optica Publishing Group
  • Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)
  • The Optical Society (Optica Publishing Group, 2019),
  • paper JT4A.9
  • https://doi.org/10.1364/BODA.2019.JT4A.9

Label-Free Intravital Imaging of Cortical Myelin in Mouse Brain by Third-Harmonic Generation Microscopy

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Abstract

We demonstrate label-free intravital imaging of the myelinated fibers in the cerebral cortex of mouse by third-harmonic generation microscopy. Using an optical parametric oscillator as the excitation source, the depth of 250 pm is achieved.

© 2019 The Author(s)

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