Near Field Optical Sensing of Single Cell Activity with Integrated Micro-Ring Resonators

Xuan Zhao; Xuan Zhao; Bo Fan; Sakib Hassan; Ashok Veeraraghavan; Ashok Veeraraghavan; Jacob T. Robinson; Jacob T. Robinson

doi:10.1364/BRAIN.2021.BTu3B.4

Biophotonics Congress 2021
OSA Technical Digest (Optica Publishing Group, 2021),
paper BTu3B.4
•https://doi.org/10.1364/BRAIN.2021.BTu3B.4

Near Field Optical Sensing of Single Cell Activity with Integrated Micro-Ring Resonators

Xuan Zhao, Bo Fan, Sakib Hassan, Ashok Veeraraghavan, and Jacob T. Robinson

Optics and the Brain 2021

Washington, DC United States
12–16 April 2021
ISBN: 978-1-943580-85-9

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Novel Optical Tools for Sensing and Manipulation of Neuronal Activity (BTu3B)

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X. Zhao, B. Fan, S. Hassan, A. Veeraraghavan, and J. T. Robinson, "Near Field Optical Sensing of Single Cell Activity with Integrated Micro-Ring Resonators," in Biophotonics Congress 2021, C. Boudoux, K. Maitland, C. Hendon, M. Wojtkowski, K. Quinn, M. Schanne-Klein, N. Durr, D. Elson, F. Cichos, L. Oddershede, V. Emiliani, O. Maragò, S. Nic Chormaic, N. Pégard, S. Gibbs, S. Vinogradov, M. Niedre, K. Samkoe, A. Devor, D. Peterka, P. Blinder, and E. Buckley, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper BTu3B.4.

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Abstract

We propose a biohybrid sensor based on optical measurements of transmembrane proteins using micro-ring resonators. The scalability and sensitivity of this geometry could enable optical recording of many individual cells over large physical areas.

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