Fiber-Based Speckle Contrast Optical Tomography for Neuroimaging in Humans: Simulation of High-Density vs. Sparse Arrays and In Vivo Human Measurements

Chen-Hao P. Lin; Chen-Hao P. Lin; Wiete Fehner; Wiete Fehner; Inema E. Orukari; Lisa Kobayashi Frisk; Alvin Agato; Alvin Agato; Manish Verma; Anthony O'Sullivan; Calamity Svoboda; Sumana Chetia; Adam T. Eggebrecht; Turgut Durduran; Turgut Durduran; Joseph P. Culver; Joseph P. Culver; Jason W. Trobaugh

doi:10.1364/BRAIN.2023.BTh2B.2

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)
Technical Digest Series (Optica Publishing Group, 2023),
paper BTh2B.2
•https://doi.org/10.1364/BRAIN.2023.BTh2B.2

Fiber-Based Speckle Contrast Optical Tomography for Neuroimaging in Humans: Simulation of High-Density vs. Sparse Arrays and In Vivo Human Measurements

Chen-Hao P. Lin, Wiete Fehner, Inema E. Orukari, Lisa Kobayashi Frisk, Alvin Agato, Manish Verma, Anthony O'Sullivan, Calamity Svoboda, Sumana Chetia, Adam T. Eggebrecht, Turgut Durduran, Joseph P. Culver, and Jason W. Trobaugh

Optics and the Brain 2023

Vancouver, British Columbia Canada
24–27 April 2023
ISBN: 978-1-957171-21-0

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Towards Translation of Optical Microscopy and Spectroscopy (BTh2B)

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C. P. Lin, W. Fehner, I. E. Orukari, L. K. Frisk, A. Agato, M. Verma, A. O'Sullivan, C. Svoboda, S. Chetia, A. T. Eggebrecht, T. Durduran, J. P. Culver, and J. W. Trobaugh, "Fiber-Based Speckle Contrast Optical Tomography for Neuroimaging in Humans: Simulation of High-Density vs. Sparse Arrays and In Vivo Human Measurements," in Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN), Technical Digest Series (Optica Publishing Group, 2023), paper BTh2B.2.

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Abstract

We simulated speckle contrast optical tomography performance based on an anatomical head model comparing sparse and high-density arrays. We also demonstrated measurements of pulsatile flow on a human head using a multi-mode fiber-based speckle system.

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