Abstract
Deep brain stimulation (DBS) surgery is performed on patients suffering Parkinson’s disease for whom medication is no longer effective in relieving their symptoms. The outcomes of the surgery are highly dependent on the placement accuracy at the targeted structure in the brain. We developed a DBS electrode that includes optical fibers to perform coherent anti-Stokes Raman scattering (CARS) spectroscopy and diffuse reflectance s pectroscopy ( DRS) d uring t he e lectrode i nsertion i n t he b rain. We w ere able to identify white and grey matter using principal component analysis (PCA), proving that spectroscopic measurements could be suitable for neuronavigation.
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