Abstract

Optical coherence tomography (OCT) has recently been developed as a new technique for high resolution measurements of biological tissue.^1,2 OCT is an extension of low coherence interferometry techniques for optical ranging measurement,^3,4 which permits the measurement of false color, cross-sectional images. OCT is particularly attractive in ophthalmic applications where it can non-invasively provide quantitative measurements of a variety of ocular diseases. We have previously demonstrated imaging of tire anterior chamber of a human eye in vitro, in cold-induced cataracts of a calf eye in vitro, in the retinal structure of a bisected human eye in vitro, and in the retinal structure of a rabbit eye in vivo. In this paper we report, as we know it, the first in vivo, transpupillary measurements of the human retina.

© 1993 Optical Society of America