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The bacterium Propionibacterium acnes (P. acnes) belongs to the normal skin flora and is involved in the pathogenesis of the wide-spread skin disease acne vulgaris. The bacterium is able to produce copro- and protoporphyrin. These endogenous porphyrins fluoresce in the red spectral region and cause autofluorescence of human skin. In vivo skin autofluorescence, in turn, can be used to evaluate the metabolism, distribution, and concentration of P. acnes.
© 1994 Optical Society of America
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