Abstract
Optical biopsy, or micron scale, cross-sectional, optical imaging of tissue micro-structure in situ, would aid the diagnosis and clinical management of many diseases. Optical coherence tomography (OCT) is a new optical imaging technique that uses low-coherence interferometry to perform high-resolution, cross -sectional imaging in biological systems.1 An important application of OCT is imaging the vascular system to identify atherosclerotic lesions that are prone to rupture.2 OCT has 10× greater resolution than state-of-the-art catheter-based ultrasonography, intravascular ultrasound (IVUS). Additional research has shown that OCT can perform imaging of other organ such as the gastrointestinal tract.3,4
© 1996 Optical Society of America
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