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  • Conference on Lasers and Electro-Optics/Quantum Electronics and Laser Science Conference and Photonic Applications Systems Technologies
  • OSA Technical Digest Series (CD) (Optica Publishing Group, 2007),
  • paper CTuP1

Multiphoton Fluorescence Imaging of NADH to Investigate Metabolic Changes in Human Epileptic Tissue in vitro

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Abstract

NADH is an intrinsic fluorophore that provides cellular metabolic information. Abnormal neuronal-astrocytic metabolic coupling is hypothesized in temporal lobe epilepsy. We investigate metabolic pathologies in human and rodent epilepsy models using multiphoton microscopy of NADH.

© 2007 Optical Society of America

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