Abstract
We discuss single-molecule detection of fluorescently-labeled proteins in solution within a nanochannel fabricated in fused silica. Confocal fluorescence microscopy and fluorescence correlation spectroscopy are employed to monitor the motion of single molecules under electrokinetic control.
© 2008 Optical Society of America
PDF ArticleMore Like This
Lloyd M. Davis, Bo Wang, Jason K. King, James A. Germann, Alexander A. Terekhov, and Brian K. Canfield
OtW3E.2 Optical Trapping Applications (OMA) 2015
Jason K. King, Lloyd M. Davis, Brian K. Canfield, Philip C. Samson, and William H. Hofmeister
FWM4 Frontiers in Optics (FiO) 2009
Quan Wang and W. E. Moerner
FTuS3 Frontiers in Optics (FiO) 2011