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Conferences > CLEOPR > 2009 > TUP > TUP14_3
  • Conference on Lasers and Electro-Optics/Pacific Rim 2009
  • (Optica Publishing Group, 2009),
  • paper TUP14_3

Investigation of Collagen Changes in Sclerodermatous Skin Using Second Harmonic Generation Microscopy

Kecheng Lu, Jianxin Chen, Shuangmu Zhuo, Liqin Zheng, Xingshan Jiang, Xiaoqin Zhu, and Jingjun Zhao

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Abstract

The changes of collagen in sclerodermatous skin were investigated qualitatively and quantitatively using second harmonic generation (SHG) microscopy. The technique has great potential to be used to diagnose scleroderma and monitor the therapy response.

© 2009 IEEE

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