Abstract
We report an optical nanopore detection system for investigating DNA translocation dynamics through a nanopore at sub-millisecond and sub-100-nm resolutions. The proposed optical nanopore detection scheme enables the observation of both the translocation process and the escape process. We found different correlation between the translocation time and the escape time, depending on whether the translocation occurs in a folded or unfolded configuration.
© 2015 IEEE
PDF ArticleMore Like This
Shaoyang Wang, Hao He, Minglie Hu, and Chingyue Wang
BT2A.6 Bio-Optics: Design and Application (BODA) 2015
Naoto Sakashita, Kento Lloyd, Tomoya Kubota, Taiki Ono, Kentaro Ishida, Toshiyuki Mitsui, and Aoyamagakuin University
30aON6 Optics and Photonics Japan (OPJ) 2017
Toshiharu Saiki, Hirohito Yamazaki, Takaha Mizuguchi, and Keiko Esashika
14p_C301_5 JSAP-OSA Joint Symposia (JSAP) 2016