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  • 2015 Conference on Lasers and Electro-Optics Pacific Rim
  • (Optica Publishing Group, 2015),
  • paper 28H2_3

Seeing an explosive way of NSF/SNAP-mediated SNARE-complex disassembly using single-molecule measurements

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Abstract

N-ethylmaleimide-sensitive factor (NSF) and alpha soluble NSF attachment protein (α-SNAP) disassemble the SNAP receptor (SNARE) complex for recycling of the SNARE proteins. Using single-molecule fluorescence and force spectroscopy, we found that NSF appears to use a “spring-loaded” mechanism.

© 2015 IEEE

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