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Conferences > CLEO_AT > 2014 > AM2P > AM2P.1

NIR fluorescent contrast agents for detection of inflammation of lungs in vivo

Haiying Zhou, Shawn He, Sean Gunsten, Steven Brody, Walter Akers, and Mikhail Y. Berezin

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Abstract

Inflammatory responses to lung injuries are mediated through enhanced production of reactive oxygen species (ROS). We describe the use of activatable NIR fluorescent agents with high sensitivity to ROS to image the lung during conditions of high inflammation.

© 2014 Optical Society of America

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