Contact lens-based sensing of lysozyme in tear fluid using a mobile well-plate reader

Zachary Ballard; Zachary Ballard; Sarah Bazargan; Diane Jung; Shyama Sathianathan; Ashley Clemens; Daniel Shir; Daniel Shir; Daniel Shir; Saba Al-Hashimi; Aydogan Ozcan; Aydogan Ozcan; Aydogan Ozcan

doi:10.1364/CLEO_AT.2021.AW3T.6

Conference on Lasers and Electro-Optics
OSA Technical Digest (Optica Publishing Group, 2021),
paper AW3T.6
•https://doi.org/10.1364/CLEO_AT.2021.AW3T.6

Contact lens-based sensing of lysozyme in tear fluid using a mobile well-plate reader

Zachary Ballard, Sarah Bazargan, Diane Jung, Shyama Sathianathan, Ashley Clemens, Daniel Shir, Saba Al-Hashimi, and Aydogan Ozcan

CLEO: Applications and Technology 2021

San Jose, California United States
9–14 May 2021
ISBN: 978-1-943580-91-0

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Advances in Compact Devices and Clinical Applications (AW3T)

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Z. Ballard, S. Bazargan, D. Jung, S. Sathianathan, A. Clemens, D. Shir, S. Al-Hashimi, and A. Ozcan, "Contact lens-based sensing of lysozyme in tear fluid using a mobile well-plate reader," in Conference on Lasers and Electro-Optics, J. Kang, S. Tomasulo, I. Ilev, D. Müller, N. Litchinitser, S. Polyakov, V. Podolskiy, J. Nunn, C. Dorrer, T. Fortier, Q. Gan, and C. Saraceno, eds., OSA Technical Digest (Optica Publishing Group, 2021), paper AW3T.6.

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Abstract

We report the quantification of lysozyme in tear fluid using contact lenses and a mobile-phone well-plate reader. We observed significantly lower lysozyme levels in human participants with dry eye disease compared to healthy controls.

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