Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Neural network-based multiplexed and micro-structured virtual staining of unlabeled tissue

Not Accessible

Your library or personal account may give you access

Abstract

We present a method to generate multiple virtual stains on an image of label-free tissue using a single deep neural network, which is fed with the autofluorescence images of the unlabeled tissue alongside a user-defined digital-staining matrix. Users can indicate which stain to apply on each pixel by editing the digital-staining matrix and blend multiple virtual stains, creating entirely new stain combinations.

© 2022 The Author(s)

PDF Article  |   Presentation Video
More Like This
Deep Learning-Based Virtual Staining of Unlabeled Tissue Samples

Kevin de Haan, Yair Rivenson, Zhensong Wei, Hongda Wang, Tairan Liu, W. Dean Wallace, and Aydogan Ozcan
MM3A.3 Microscopy Histopathology and Analytics (Microscopy) 2020

Virtual histological stain transformations through cascaded deep neural networks

Xilin Yang, Bijie Bai, Yuzhu Li, Yijie Zhang, Tairan Liu, Kevin de Haan, and Aydogan Ozcan
FTh3B.1 Frontiers in Optics (FiO) 2022

Deep learning-based transformation of H&E stained tissue into special stains

Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman, Tairan Liu, Yair Rivenson, W. Dean Wallace, and Aydogan Ozcan
ATh2I.4 CLEO: Applications and Technology (CLEO:A&T) 2022

Presentation Video

Presentation video access is available to:

  1. Optica Publishing Group subscribers
  2. Technical meeting attendees
  3. Optica members who wish to use one of their free downloads. Please download the article first. After downloading, please refresh this page.

Contact your librarian or system administrator
or
Log in to access Optica Member Subscription or free downloads


More Like This
Deep Learning-Based Virtual Staining of Unlabeled Tissue Samples

Kevin de Haan, Yair Rivenson, Zhensong Wei, Hongda Wang, Tairan Liu, W. Dean Wallace, and Aydogan Ozcan
MM3A.3 Microscopy Histopathology and Analytics (Microscopy) 2020

Virtual histological stain transformations through cascaded deep neural networks

Xilin Yang, Bijie Bai, Yuzhu Li, Yijie Zhang, Tairan Liu, Kevin de Haan, and Aydogan Ozcan
FTh3B.1 Frontiers in Optics (FiO) 2022

Deep learning-based transformation of H&E stained tissue into special stains

Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman, Tairan Liu, Yair Rivenson, W. Dean Wallace, and Aydogan Ozcan
ATh2I.4 CLEO: Applications and Technology (CLEO:A&T) 2022

Neural network-based virtual staining of defocused autofluorescence images of label-free tissue

Yijie Zhang, Luzhe Huang, Tairan Liu, Keyi Cheng, Kevin de Haan, Yuzhu Li, Bijie Bai, and Aydogan Ozcan
ATu3Q.1 CLEO: Applications and Technology (CLEO:A&T) 2023

Deep Learning-based Virtual Immunohistochemical HER2 staining of Label-Free Breast Tissue

Bijie Bai, Hongda Wang, Yuzhu Li, Kevin de Haan, Francesco Colonnese, Yujie Wan, Jingyi Zuo, Ngan B. Doan, Xiaoran Zhang, Yijie Zhang, Jingxi Li, Wenjie Dong, Morgan Angus Darrow, Elham Kamangar, Han Sung Lee, Yair Rivenson, and Aydogan Ozcan
SM5O.2 CLEO: Science and Innovations (CLEO:S&I) 2022

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved