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Conferences > CLEO_AT > 2022 > ATu5I > ATu5I.2

Longitudinal Deep-Brain Imaging through an Intact Skull Using a Label-Free Reflection Matrix Microscopy

Yongwoo Kwon, Seokchan Yoon, Jin Hee Hong, Hojun Lee, and Wonshik Choi

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Abstract

We implemented a label-free reflection matrix microscopy system using a 1.3-μm wavelength pulsed laser and conducted in vivo imaging of a 3- to 10-week-old mouse brain with an intact skull. The myelination processes at the early developmental stages were observed up to the cortical layer IV with the ideal diffraction-limited resolution of 650 nm.

© 2022 The Author(s)

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